Buy Reductil - Redumin (Sibutramine Hydrochloride) (60 Tabs/15mg)

Redumin/Reductil contains the active ingredient sibutramine hydrochloride monohydrate, which is a type of anti-obesity medicine. It works by affecting neurotransmitters in the brain.

Neurotransmitters are chemicals that are stored in nerve cells and are involved in transmitting messages between the nerve cells. They are released from nerve cells as a message is transmitted. Once the message has been transmitted, the nerve cells then reabsorb the neurotransmitter.

Sibutramine prevents two of these neurotransmitters, noradrenaline and serotonin, from being reabsorbed back into the nerve cells. Noradrenaline and serotonin are responsible for moderating mood and various other processes in the brain. It is thought that sibutramine helps people to lose weight by increasing the amount of noradrenaline and serotonin free to act in the brain. This enhances the feeling of fulfillment from eating, and so makes you feel satisfied after eating less food.

Redumin/Reductil (Sibutramine) is only licensed to aid weight loss in people with a body mass index (BMI) of 30 or higher, and those with a BMI of 27 or higher who also have other obesity related risk factors, such as type 2 diabetes or high cholesterol. It is only prescribed to people in these categories who have had difficulty achieving or maintaining weight loss of more than five per cent of their body weight over three months, using conventional weight loss programmes alone (eg diet and exercise).

How does Reductil work?

How effective is Reductil?

Three studies have evaluated Redumin/Reductil over a period of 12 months in 1,628 patients with obesity. When used in combination with a reduced-calorie diet and appropriate physical activity, 77% of Redumin/Reductil patients achieved weight loss that benefited their health.

In the first study - patients treated with Redumin/Reductil were compared with patients given a placebo. After 12 months, those taking Redumin/Reductil sustained a net weight loss of 5.2 kg compared with a gain of 0.5 kg with placebo.

In the second study - patients who had already lost at least 2% of body weight or 2 kg after 4 weeks' treatment with Redumin/Reductil were split into 2 groups. Group A continued to take Redumin/Reductil; and Group B were given a placebo for a further 48 weeks. Mean weight loss during the 48-week treatment period with Redumin/Reductil was 3.8 kg (4%) compared with a gain of 0.2 kg (0.2%) with placebo.

In the third study - patients who achieved more than 5% weight loss with Redumin/Reductil after 6 months were studied. Patients taking Redumin/Reductil maintained most of their weight loss after a further 6 months, after which mean weight began to increase; by contrast, those given a placebo immediately began to gain weight. After 18 months, 42% of patients treated with Redumin/Reductil had maintained at least 80% of weight loss compared with 16% of those with placebo.

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